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A Chronically Implantable Bidirectional Neural Interface for Non-human Primates

Chronically implantable photostimulation device

Fabrication of micro-LED array
The chronically implantable micro-LED array (Figure ​(Figure1)1) was manufactured
by Cir-Tech Inc. (Shizuoka, Japan) for optical stimulations.
The base of the array, made of a thin, flexible, circuit board material,
consisted of a layer of polyimide film sandwiched between two copper layers.
The copper layer on one side was dry etched for wiring the LED to the connector,
and the copper layer on the other side was shaped for an electric shield.
The copper layers were insulated with a polyimide film attached with glue.
Then, holes were made by laser drilling at the desired locations and LEDs
(ES-CEBHV13; EPISTAR Corp., Hsinchu, Taiwan) were installed in the holes.
Finally, all the LEDs were sealed with transparent resin.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605616/#!po=16.6667


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